Integrated Center for Oncology

Breast Cancer Gene-Expression Miner v4.5
(bc-GenExMiner v4.5)

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What's new?



Please note and cite our new website address: http://bcgenex.ico.unicancer.fr
  • Find here a chronological listing of bc-GenExMiner versions.

  • Gene symbol and probeset annotations of datasets are regularly actualised* to offer up-to-date tool.

    Evolution of bc-GenExMiner will mainly consist in the inclusion of new annotated genomic datasets and new data mining functions.

    *: web databases source (GeneCards, Source, Unigene...)


    bc-GenExMiner version Date Main evolution Updated data No. new patients No. datasets New functionalities
    DNA microarray RNA-seq DNA microarray RNA-seq
    New 4.5 2020/06/22 Correlation module updated ---   527   1 234  Targeted module: PR, ER/PR, PAM50, Basal-like/TNBC, and TNBC subtypes population criterion added.
    Exhaustive module: 8 population criteria added + updated results display.
    Chromosomal location module: 8 population criteria added + updated results display.
    Expression module updated Targeted module: 3 population criteria added: nature of the tissue, TNBC subtypes and integrative clusters.
    Exhaustive module: 3 population criteria added (see targeted module).
    Customised module: discretisation option added.
    Prognostic module updated Targeted module: PR population criterion added, mixed choice rename to all, one event added and rename all event status to 'DMFS', 'OS' and 'DFS'.
    Exhaustive module: one event added and rename all event status to 'DMFS', 'OS' and 'DFS' + updated results display.
    Intrinsic molecular subtypes module: possibility to choose between 3 population events: 'DMFS', 'OS' and 'DFS' + deep update of results display.
    Basal-like & TNBC module: one event added and rename all event status to 'DMFS', 'OS' and 'DFS' + updated results display (exhaustive event status analysis done).
    4.4 2019/12/09 Correlation module updated ---   ---   ---  Targeted module: correlation analyses of up to 20 genes can be performed at one time.
    Expression module updated Two new population criteria have been added: histological types and P53 status.
    Three new types of figure have been added:
    beeswarm, violin and raincloud plots.
    Customised module: new gene expression data added (Affymetrix™, Metabric, TCGA, GSE81540).
    Prognostic module updated Targeted module: two versions of Kaplan-Meier curve are available (with or without tick marks).
    Genes annotation updated
    830   ---  
    4.3 2019/07/05 New cohorts have been added to database (DNA microarrays and RNA-seq).
    ---   4 305   4 712  ---  
    4.2.1 2019/06/18 Expression and correlation modules updated
    ---   ---   ---  ---  Figure files available in EMF format.
    4.2 2019/01/09 All modules updated
    ---   ---   ---  ---  Automatic dropdown list of stored gene symbols.
    Help for choosing Affymetrix™ probes by using the gene symbol with several options (median, highest ou JetSet probe).
    Prognostic module updated
    Discretisation options added. Figure files available in EMF format.
    Genes annotation updated
    1 354   ---  
    4.1 2017/12/14 Genes annotation updated 4 823   ---   ---  ---  ---
    4.0 2016/03/30 Expression module added
    ---   ---   ---  ---  Expression analyses: targeted, exhaustive and customised
    New type of analysis added
    Prognostic analysis: Basal-like and/or TNBC
    Targeted correlation analysis: Basal-like and/or TNBC
    3.2 2015/09/04 Genes annotation updated 3 441   ---   ---  ---  ---
    3.1 2014/12/11 New cohorts have been added to database ---   2 486   ---  ---  ---
    Genes annotation updated 3 829   ---   ---  ---  ---
    3.0 2014/03/07 New type of figure added
    ---   ---   ---  ---  Box and whiskers plot figure corresponding to molecular subtype gene-expression map
    3.0 2012/02/15 Correlation module added
    ---   ---   ---  ---  Correlation analyses: targeted, exhaustive and by chromosomal location
    2.1 2011/08/01 Genes annotation updated
    637   ---   ---  ---  ---
    2.0 2011/01/26 New type of analysis added
    2 320   ---   ---  ---  Prognostic analysis: molecular subtype
    1.1 2010/08/02 New cohorts have been added to database
    1 359   336   ---  ---  ---
    1.0 2010/02/05 bc-GenExMiner v1.0 launching
    1 325   ---   ---  ---  Prognostic analyses: targeted and exhaustive


    Legend Open

     TNBC:triple-negative breast cancer
     Updated data:number of updated gene symbols and probesets



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